Gender as a term is a logical means for creating awareness about inequalities perverted due to institutional structures in many societies across the world. The aim of this study was to assess health and safety and the gender gap: the need for women’s involvement in Port Harcourt Metropolis. A descriptive cross-sectional survey was adopted for this study. The population for this study comprised of estimated workers from various industrial companies in Port Harcourt Metropolis. A sample size of 500 was calculated using the Taro Yamane formula for a large population. A multi-stage sampling procedure was adopted for this study. The instrument for data collection was a self-structured questionnaire Data collected was analyzed with Statistical Product for the Service Solutions (SPSS) using the descriptive statistics of frequency and percentages (%). The finding of the study revealed that 398(82.7%) of the respondents who participated in health and safety were males while 83(17.3%) were females. The finding also showed that there was significant difference in health and safety involvement based on gender among workers in construction companies in Port Harcourt Metropolis (X²–value = 51.175; df = 1, p<0.05). The study concluded that there was a very large gap among gender in the safety profession with women being affected; therefore, there is need for women to be encouraged to participate and get involved in safety education, recruitment and enrollment in safety educational courses and or programmes. The study recommended amongst others that safety stakeholders and relevant agencies should ensure diversity and inclusion of all gender to make workplaces safer and further protect a greater number of employees from injuries and fatalities.