The present paper deals with the radical unstoppable continuous conflicts of the 21^st Century occurring in the hot spot of Africa specially in the Great Lakes Region including the DRC and Rwanda as factional groups keeps using their locally fabricated and imported arms of different categories to slaughter the unarmed civilians to the benefits of the Western hyper neo-colonial actors. The latters are the promoter of skirmishes to open conflict situations which could facilitate their massive exploitation of natural resources in the context of CUCWWEA. Over thousands of their countrymen have lost their lives, internal and external displacements and frustration round the clock which means nothing to the war treasurers and promoters in the game of war economy interests. For long will the Africans of that specific region know the realities  and values of human being is still a question that worries and leaders of the said countries have to sit-up in the truthful negotiation table to find an everlasting solution knowing that the West remains what they are in their manipulation agenda the African Continent cutting across slavery and slave trade, indelible crimes committed during the era of colonization in different African colonial territories conferred to them out of the November 1884 and February 1885 Berlin Colonial Conference and thereafter, the aftermaths of the first and second world wars with the Mandated and Trusteeship Systems of the League of nations and United Nations in 1919 and 1945 respectively. In fact, the cheating or unequal globalization slogans between the Industrialized Developed World (IDW) and Remote Industrialized Less Developed World (RILDW) who are in high needs of African natural resources at all course is a clear indication that any approaches brought in for conflict management, negotiation, arbitration and pacific settlement in any act of aggression and breach of peace may however ends up in pieces of much troubles so far as their interests is tempered with. Therefore, Africans should understand themselves in the ancient palaver settle approaches vis-à-vis the contemporary mechanisms to prevent themselves from being wanted all the times as criminals when power elapses with the conspiracy of any Western initiatives. Using the historical perspectives in the analyses, with modest experiences in the lecturing of Africa in International Relations in the post-graduate levels, the used of specialized sources, documentaries and valuable website sources provided us with enormous authentic evidence concerning the challenges of the 21^st Century still unresolvable in the Hot Spot of African Conflict of the Economic Community of Central African States(ECCAS).