This study investigated School Safety Management (SSM) and its implications for effective teaching and learning in insecure environments in Nigeria. The research aimed to identify the dominant SSM strategies implemented in selected schools, examine their impact on teachers’ professional competencies, and assess the influence of the SSM environment on students’ academic development indicators. A descriptive survey research design was adopted, involving a population of 19,200 teachers and students, from which 392 respondents were selected using a multistage sampling technique. Data were collected via a structured questionnaire and analyzed using mean, standard deviation, and regression analysis. Findings revealed that SSM strategies, including safety policies, teacher training, emergency preparedness, and collaboration with security agencies, were widely implemented and had a significant positive impact on teachers’ professional competencies. Similarly, the SSM environment significantly enhanced students’ academic engagement, psychosocial well-being, and learning outcomes. The study concluded that robust safety management practices are critical for creating conducive teaching and learning conditions in insecure school settings. Recommendations include the implementation of comprehensive safety policies, continuous training for teachers and students, and strengthened collaboration with local security agencies.